Development and transdifferentiation into inner hair cells require Tbx2

Atoh1 is essential for the development of both outer hair cells (OHCs) and inner hair cells (IHCs) in the mammalian cochlea. Whereas Ikzf2 is necessary for OHC development, the key gene required for IHC development remains unknown. We found that deletion of Tbx2 in neonatal IHCs led to their transdi...

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Detalles Bibliográficos
Autores principales: Bi, Zhenghong, Li, Xiang, Ren, Minhui, Gu, Yunpeng, Zhu, Tong, Li, Shuting, Wang, Guangqin, Sun, Suhong, Sun, Yuwei, Liu, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844247/
https://www.ncbi.nlm.nih.gov/pubmed/36687561
http://dx.doi.org/10.1093/nsr/nwac156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844247/
https://www.ncbi.nlm.nih.gov/pubmed/36687561
http://dx.doi.org/10.1093/nsr/nwac156

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