Portability of Polygenic Risk Scores for Sleep Duration, Insomnia and Chronotype in 33,493 Individuals

Polygenic risk scores (PRSs) estimate genetic liability for diseases and traits. However, the portability of PRSs in sleep traits has remained elusive. We generated PRSs for self-reported insomnia, chronotype and sleep duration using summary data from genome-wide association studies (GWASs) performe...

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Detalles Bibliográficos
Autores principales: Perkiö, Anna, Merikanto, Ilona, Kantojärvi, Katri, Paunio, Tiina, Sinnott-Armstrong, Nasa, Jones, Samuel E., Ollila, Hanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844282/
https://www.ncbi.nlm.nih.gov/pubmed/36648941
http://dx.doi.org/10.3390/clockssleep5010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844282/
https://www.ncbi.nlm.nih.gov/pubmed/36648941
http://dx.doi.org/10.3390/clockssleep5010002

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