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Portability of Polygenic Risk Scores for Sleep Duration, Insomnia and Chronotype in 33,493 Individuals
Polygenic risk scores (PRSs) estimate genetic liability for diseases and traits. However, the portability of PRSs in sleep traits has remained elusive. We generated PRSs for self-reported insomnia, chronotype and sleep duration using summary data from genome-wide association studies (GWASs) performe...
Autores principales: | Perkiö, Anna, Merikanto, Ilona, Kantojärvi, Katri, Paunio, Tiina, Sinnott-Armstrong, Nasa, Jones, Samuel E., Ollila, Hanna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844282/ https://www.ncbi.nlm.nih.gov/pubmed/36648941 http://dx.doi.org/10.3390/clockssleep5010002 |
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