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Distribution and favorable prognostic implication of genomic EGFR alterations in IDH ‐wildtype glioblastoma

BACKGROUND: We aimed to evaluate the mutation profile, transcriptional variants, and prognostic impact of the epidermal growth factor receptor (EGFR) gene in isocitrate dehydrogenase (IDH)‐wildtype glioblastomas (GBMs). METHODS: We sequenced EGFR, evaluated the EGFR splicing profile using a next‐gen...

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Detalles Bibliográficos
Autores principales: Higa, Nayuta, Akahane, Toshiaki, Hamada, Taiji, Yonezawa, Hajime, Uchida, Hiroyuki, Makino, Ryutaro, Watanabe, Shoji, Takajo, Tomoko, Yokoyama, Seiya, Kirishima, Mari, Matsuo, Kei, Fujio, Shingo, Hanaya, Ryosuke, Tanimoto, Akihide, Yoshimoto, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844636/
https://www.ncbi.nlm.nih.gov/pubmed/35695190
http://dx.doi.org/10.1002/cam4.4939