The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration

Tissue-specific transcription factors (TFs) control the transcriptome through an association with noncoding regulatory regions (cistromes). Identifying the combination of TFs that dictate specific cell fate, their specific cistromes and examining their involvement in complex human traits remain a ma...

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Detalles Bibliográficos
Autores principales: Cohen-Gulkar, Mazal, David, Ahuvit, Messika-Gold, Naama, Eshel, Mai, Ovadia, Shai, Zuk-Bar, Nitay, Idelson, Maria, Cohen-Tayar, Yamit, Reubinoff, Benjamin, Ziv, Tamar, Shamay, Meir, Elkon, Ran, Ashery-Padan, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844853/
https://www.ncbi.nlm.nih.gov/pubmed/36649236
http://dx.doi.org/10.1371/journal.pbio.3001924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844853/
https://www.ncbi.nlm.nih.gov/pubmed/36649236
http://dx.doi.org/10.1371/journal.pbio.3001924

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