The PTP1B selective inhibitor MSI-1436 mitigates Tunicamycin-induced ER stress in human hepatocarcinoma cell line through XBP1 splicing modulation

Protein tyrosine phosphatase PTP1B is considered as a key metabolic enzyme that has been reported to be associated with insulin resistance onset, and underlying cellular metabolic malfunctions, including ER stress and mitochondrial failure. In this study, effects of selective PTP1B inhibition using...

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Detalles Bibliográficos
Autores principales: Bourebaba, Lynda, Komakula, Sai Santosh Babu, Weiss, Christine, Adrar, Nabil, Marycz, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844924/
https://www.ncbi.nlm.nih.gov/pubmed/36649358
http://dx.doi.org/10.1371/journal.pone.0278566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844924/
https://www.ncbi.nlm.nih.gov/pubmed/36649358
http://dx.doi.org/10.1371/journal.pone.0278566

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