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Sex and prior exposure jointly shape innate immune responses to a live herpesvirus vaccine

BACKGROUND: Both sex and prior exposure to pathogens are known to influence responses to immune challenges, but their combined effects are not well established in humans, particularly in early innate responses critical for shaping subsequent outcomes. METHODS: We employed systems immunology approach...

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Detalles Bibliográficos
Autores principales: Cheung, Foo, Apps, Richard, Dropulic, Lesia, Kotliarov, Yuri, Chen, Jinguo, Jordan, Tristan, Langweiler, Marc, Candia, Julian, Biancotto, Angelique, Han, Kyu Lee, Rachmaninoff, Nicholas, Pietz, Harlan, Wang, Kening, Tsang, John S, Cohen, Jeffrey I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844983/
https://www.ncbi.nlm.nih.gov/pubmed/36648132
http://dx.doi.org/10.7554/eLife.80652