Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice

In previous study, we showed that nucleolar protein 66 (NO66) is a chromatin modifier and negatively regulates Osterix activity as well as mesenchymal progenitor differentiation. Genetic ablation of the NO66 (RIOX1) gene in cells of the Prx1-expressing mesenchymal lineage leads to acceleration of os...

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Detalles Bibliográficos
Autores principales: Chen, Qin, Sinha, Krishna M., de Crombrugghe, Benoit, Krahe, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845042/
https://www.ncbi.nlm.nih.gov/pubmed/36660551
http://dx.doi.org/10.1155/2023/8998556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845042/
https://www.ncbi.nlm.nih.gov/pubmed/36660551
http://dx.doi.org/10.1155/2023/8998556

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