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Construction and stable gene expression of AGR2xPD1 bi-specific antibody that enhances attachment between T-Cells and lung tumor cells, suppress tumor cell migration and promoting CD8 expression in cytotoxic T-cells

There has been a substantial and consistent rise in the number of clinical trials to develop advanced and potent bispecific antibodies (BsAb) over the past two decades with multiple targets to improve the efficacy or tissue specificity of monoclonal antibodies (mAb) treatment for diseases with multi...

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Detalles Bibliográficos
Autores principales: Roy, Debmalya, Liu, Guo-Song, Zeling Wang, Aru, Zhou, Bingjie, Yunus, Fakhar-Un-Nisa, Raza, Ghulam, Bharath Merugu, Siva, Saidi Mashausi, Dhahiri, Li, Dawei, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845114/
https://www.ncbi.nlm.nih.gov/pubmed/36685298
http://dx.doi.org/10.1016/j.jsps.2022.11.007