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Temporal offset association between the number of irinotecan-related adverse reactions and pharmacogenomic studies: A cross-correlation analysis

OBJECTIVES: Studies have proved that UGT1A1 (*6, *28 and *93) gene polymorphism was closely related to the side effects of irinotecan. This study intends to perform a correlation analysis on the relationship between pharmacogenomic studies and ADRs based on time series. METHODS: The ADRs related to...

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Detalles Bibliográficos
Autores principales: Kong, Lingti, Rong, Li, Xie, Mengyuan, Wang, Muhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845122/
https://www.ncbi.nlm.nih.gov/pubmed/36685299
http://dx.doi.org/10.1016/j.jsps.2022.11.016