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Cathepsin-B inhibitor CA-074 attenuates retinopathy and optic neuritis in experimental autoimmune encephalomyelitis induced in SJL/J mice

The complicated multiple sclerosis (MS) can exhibit subacute sight deterioration and can lead to total deprivation of vision. In the current work, we explored the therapeutic outcome of Cathepsin B inhibitor (CA-074) against retinopathy and optic neuritis (ON) caused by experimental autoimmune encep...

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Detalles Bibliográficos
Autores principales: Rashid Khan, Mohammad, Fayaz Ahmad, Sheikh, Nadeem, Ahmed, Imam, Faisal, Al-Harbi, Naif O., Shahnawaz Khan, Mohd, Alsahli, Meshal, Alhosaini, Khaled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845124/
https://www.ncbi.nlm.nih.gov/pubmed/36685301
http://dx.doi.org/10.1016/j.jsps.2022.11.013