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A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma

Mixed lineage kinase domain-like (MLKL) is widely accepted as an executioner of necroptosis, in which MLKL mediates necroptotic signaling and triggers cell death in a receptor-interacting protein kinase 3 (RIPK3)-dependent manner. Recently, it is increasingly noted that RIPK3 is intrinsically silenc...

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Detalles Bibliográficos
Autores principales: Jiang, Xifei, Deng, Wenjia, Tao, Siyao, Tang, Zheng, Chen, Yuehong, Tian, Mengxin, Wang, Ting, Tao, Chenyang, Li, Yize, Fang, Yuan, Pu, Congying, Gao, Jun, Wang, Xiaomin, Qu, Weifeng, Gai, Xiameng, Ding, Zhenbin, Fu, Yixian, Zheng, Ying, Cao, Siyuwei, Zhou, Jian, Huang, Min, Liu, Weiren, Xu, Jun, Fan, Jia, Shi, Yinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845215/
https://www.ncbi.nlm.nih.gov/pubmed/36650126
http://dx.doi.org/10.1038/s41421-022-00504-0