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Efficient gene–environment interaction testing through bootstrap aggregating

Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential interplay between several genetic loci. Approach...

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Detalles Bibliográficos
Autores principales: Lau, Michael, Kress, Sara, Schikowski, Tamara, Schwender, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845231/
https://www.ncbi.nlm.nih.gov/pubmed/36650248
http://dx.doi.org/10.1038/s41598-023-28172-4