High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform

Telomeres are specialized nucleoprotein structures at the ends of linear chromosomes. The progressive shortening of steady-state telomere length in normal human somatic cells is a promising biomarker for age-associated diseases. However, there remain substantial challenges in quantifying telomere le...

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Detalles Bibliográficos
Autores principales: Tham, Cheng-Yong, Poon, LaiFong, Yan, TingDong, Koh, Javier Yu Peng, Ramlee, Muhammad Khairul, Teoh, Vania Swee Imm, Zhang, Suihan, Cai, Yi, Hong, Zebin, Lee, Gina S., Liu, Jin, Song, Hai Wei, Hwang, William Ying Khee, Teh, Bin Tean, Tan, Patrick, Xu, Lifeng, Koh, Angela S., Osato, Motomi, Li, Shang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845338/
https://www.ncbi.nlm.nih.gov/pubmed/36650155
http://dx.doi.org/10.1038/s41467-023-35823-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845338/
https://www.ncbi.nlm.nih.gov/pubmed/36650155
http://dx.doi.org/10.1038/s41467-023-35823-7

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