Transcriptional vulnerabilities of striatal neurons in human and rodent models of Huntington’s disease

Striatal projection neurons (SPNs), which progressively degenerate in human patients with Huntington’s disease (HD), are classified along two axes: the canonical direct-indirect pathway division and the striosome-matrix compartmentation. It is well established that the indirect-pathway SPNs are susc...

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Detalles Bibliográficos
Autores principales: Matsushima, Ayano, Pineda, Sergio Sebastian, Crittenden, Jill R., Lee, Hyeseung, Galani, Kyriakitsa, Mantero, Julio, Tombaugh, Geoffrey, Kellis, Manolis, Heiman, Myriam, Graybiel, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845362/
https://www.ncbi.nlm.nih.gov/pubmed/36650127
http://dx.doi.org/10.1038/s41467-022-35752-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845362/
https://www.ncbi.nlm.nih.gov/pubmed/36650127
http://dx.doi.org/10.1038/s41467-022-35752-x

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