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Modulations of the neuronal trafficking of tissue-type plasminogen activator (tPA) influences glutamate release

The discovery of the neuronal expression of the serine protease tissue-type plasminogen activator (tPA) has opened new avenues of research, with important implications in the physiopathology of the central nervous system. For example, the interaction of tPA with synaptic receptors (NMDAR, LRP1, Anne...

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Detalles Bibliográficos
Autores principales: Varangot, Alexandre, Lebatard, Simon, Bellemain-Sagnard, Mathys, Lebouvier, Laurent, Hommet, Yannick, Vivien, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845363/
https://www.ncbi.nlm.nih.gov/pubmed/36650132
http://dx.doi.org/10.1038/s41419-022-05543-9