Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization and function in CT26 tumor-bearing mice

Macrophages are a major population of immune cells in solid cancers, especially colorectal cancers. Tumor-associated macrophages (TAMs) are commonly divided into M1-like (tumor suppression) and M2-like (tumor promotion) phenotypes. Vasoactive intestinal peptide (VIP) is an immunoregulatory neuropept...

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Detalles Bibliográficos
Autores principales: Kittikulsuth, Wararat, Nakano, Daisuke, Kitada, Kento, Uyama, Toru, Ueda, Natsuo, Asano, Eisuke, Okano, Keiichi, Matsuda, Yoko, Nishiyama, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845384/
https://www.ncbi.nlm.nih.gov/pubmed/36650220
http://dx.doi.org/10.1038/s41598-023-28073-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845384/
https://www.ncbi.nlm.nih.gov/pubmed/36650220
http://dx.doi.org/10.1038/s41598-023-28073-6

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