New natural compound inhibitors of PDGFRA (platelet-derived growth factor receptor α) based on computational study for high−grade glioma therapy

BACKGROUND: High-grade glioma (HGG) is a malignant brain tumor that is common and aggressive in children and adults. In the current medical paradigm, surgery and radiotherapy are the standard treatments for HGG patients. Despite this, the overall prognosis is still very bleak. Studies have shown tha...

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Detalles Bibliográficos
Autores principales: Yang, Wenzhuo, Wang, Shengnan, Zhang, Xiangmao, Sun, Hu, Zhang, Menghan, Chen, Hongyu, Cui, Junxiang, Li, Jinyang, Peng, Fei, Zhu, Mingqin, Yu, Bingcheng, Li, Yifan, Yang, Liu, Min, Wanwan, Xue, Mengru, Pan, Lin, Zhu, Hao, Wu, Bo, Gu, Yinghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845622/
https://www.ncbi.nlm.nih.gov/pubmed/36685223
http://dx.doi.org/10.3389/fnins.2022.1060012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845622/
https://www.ncbi.nlm.nih.gov/pubmed/36685223
http://dx.doi.org/10.3389/fnins.2022.1060012

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