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Collagen VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche

Pancreatic cancer is a deadly and highly metastatic disease, although how metastatic lesions establish is not fully understood. A key feature of pancreatic tumours is extensive fibrosis and deposition of extracellular matrix (ECM). While pancreatic cancer cells are programmed by stimuli derived from...

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Detalles Bibliográficos
Autores principales: Papalazarou, Vasileios, Drew, James, Juin, Amelie, Spence, Heather J., Whitelaw, Jamie, Nixon, Colin, Salmeron-Sanchez, Manuel, Machesky, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845737/
https://www.ncbi.nlm.nih.gov/pubmed/36546396
http://dx.doi.org/10.1242/jcs.259978