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m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis

The dysregulation of autophagy contributes to renal fibrosis. N6-Methyladenosine (m6A) RNA modification is a critical mediator of autophagy. Our previous studies have reported that the disorder of the PPARα/fatty acid oxidation (FAO) axis in renal tubular cells is suppressed by STAT6, which is invol...

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Detalles Bibliográficos
Autores principales: Yang, Youjing, Li, Qianmin, Ling, Yi, Leng, Linxin, Ma, Yu, Xue, Lian, Lu, Guoyuan, Ding, Yue, Li, Jianzhong, Tao, Shasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845768/
https://www.ncbi.nlm.nih.gov/pubmed/36685533
http://dx.doi.org/10.3389/fimmu.2022.1094556