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Assessing the role of membrane lipids in the action of ruthenium(III) anticancer compounds

This work addresses the possible role of the cell membrane in the molecular mechanism of action of two salan-type ruthenium complexes that were previously shown to be active against human tumor cells, namely [Ru(III)(L1)(PPh(3))Cl] and [Ru(III)(L2)(PPh(3))Cl] (where L1 is 6,6′-(1R,2R)-cyclohexane-1,...

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Detalles Bibliográficos
Autores principales: Starosta, Radoslaw, Santos, Telma C., Dinis de Sousa, Andreia F., Santos, Maria Soledade, Corvo, M. Luisa, Tomaz, Ana Isabel, de Almeida, Rodrigo F. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845782/
https://www.ncbi.nlm.nih.gov/pubmed/36660430
http://dx.doi.org/10.3389/fmolb.2022.1059116