A novel coumarin-triazole-thiophene hybrid: synthesis, characterization, ADMET prediction, molecular docking and molecular dynamics studies with a series of SARS-CoV-2 proteins

Synthesis, characterization and theoretical studies of a novel coumarin-triazole-thiophene hybrid 4-(((4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)methyl)-6,7-dimethyl-2H-chromen-2-one (1), which was fabricated from 4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazole-3-thiol and 4-(chloromethyl)-6,...

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Detalles Bibliográficos
Autores principales: Omar, Rebaz Anwar, Koparir, Pelin, Sarac, Kamuran, Koparir, Metin, Safin, Damir A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2023
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845830/
https://www.ncbi.nlm.nih.gov/pubmed/36686402
http://dx.doi.org/10.1007/s12039-022-02127-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845830/
https://www.ncbi.nlm.nih.gov/pubmed/36686402
http://dx.doi.org/10.1007/s12039-022-02127-0

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