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SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet procoagulant activity

Thrombosis of the lung microvasculature is a characteristic of COVID-19 disease, which is observed in large excess compared to other forms of acute respiratory distress syndrome and thus suggests a trigger for thrombosis that is endogenous to the lung. Our recent work has shown that the SARS-CoV-2 S...

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Detalles Bibliográficos
Autores principales: Cappelletto, Ambra, Allan, Harriet E., Crescente, Marilena, Schneider, Edoardo, Bussani, Rossana, Ali, Hashim, Secco, Ilaria, Vodret, Simone, Simeone, Roberto, Mascaretti, Luca, Zacchigna, Serena, Warner, Timothy D., Giacca, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845929/
https://www.ncbi.nlm.nih.gov/pubmed/36684586
http://dx.doi.org/10.3389/fcvm.2022.1013262