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Implications of BRAF V600E mutation in gliomas: Molecular considerations, prognostic value and treatment evolution

Gliomas are molecularly heterogeneous brain tumors responsible for the most years of life lost by any cancer. High-grade gliomas have a poor prognosis and despite multimodal treatment including surgery, radiotherapy, and chemotherapy, exhibit a high recurrence rate. There is a need for new therapeut...

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Detalles Bibliográficos
Autores principales: Di Nunno, Vincenzo, Gatto, Lidia, Tosoni, Alicia, Bartolini, Stefania, Franceschi, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846085/
https://www.ncbi.nlm.nih.gov/pubmed/36686797
http://dx.doi.org/10.3389/fonc.2022.1067252