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Reduced mitochondrial DNA content correlate with poor clinical outcomes in cryotransfers with day 6 single euploid embryos

OBJECTIVE: To investigate whether the mitochondrial DNA (mtDNA) content of a single biopsy at trophoblast correlates with the developmental potential and reproductive outcomes of blastocyst. METHODS: A retrospective analysis applied the dataset of 1,675 embryos with preimplantation genetic testing f...

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Detalles Bibliográficos
Autores principales: Chuang, Tzu-Hsuan, Chen, Chih-Yen, Kuan, Chin-Sheng, Lai, Hsing-Hua, Hsieh, Chia-Lin, Lee, Meng-Ju, Liang, Yi-Ting, Chang, Yu-Jen, Chen, Chien-Yu, Chen, Shee-Uan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846089/
https://www.ncbi.nlm.nih.gov/pubmed/36686452
http://dx.doi.org/10.3389/fendo.2022.1066530