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An intrasplenic injection model of pancreatic cancer metastasis to the liver in mice

Here, we provide a protocol for an intrasplenic injection model to establish pancreatic tumors in the mouse liver. We describe the steps to inject tumor cells into mouse spleen and to perform a splenectomy, followed by animal recovery and end point analysis of tumors in the liver. This model allows...

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Detalles Bibliográficos
Autores principales: O’Brien, Megan, Ernst, Matthias, Poh, Ashleigh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846119/
https://www.ncbi.nlm.nih.gov/pubmed/36638017
http://dx.doi.org/10.1016/j.xpro.2022.102021