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Modulation of GABA(B) receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks

BACKGROUND: Stimulation of gamma-aminobutyric acid (GABA) activity through GABA receptor agonists is the basic mechanism of many anticonvulsant drugs. Nevertheless, many of these GABergic drugs have adverse cognitive effects. We previously found that GABAB receptors (GABA(B)Rs) in the insula regulat...

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Detalles Bibliográficos
Autores principales: Wu, Nan, Sun, Tao, Wu, Xin, Chen, Hongguang, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846148/
https://www.ncbi.nlm.nih.gov/pubmed/36688127
http://dx.doi.org/10.3389/fnbeh.2022.1042227