Echinacoside exerts antidepressant-like effects through enhancing BDNF-CREB pathway and inhibiting neuroinflammation via regulating microglia M1/M2 polarization and JAK1/STAT3 pathway

The present study was performed to investigate the antidepressant effect of echinacoside (ECH) using chronic unpredictable mild stress (CUMS) induced depression mice and lipopolysaccharide (LPS)-stimulated N9 microglial cells. CUMS treatment was performed on C57BL/6 mice for 28 days, followed by gav...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Renrui, Zhang, Li, Wang, Huihui, Li, Meng, Feng, Weisheng, Zheng, Xiaoke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846169/
https://www.ncbi.nlm.nih.gov/pubmed/36686689
http://dx.doi.org/10.3389/fphar.2022.993483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846169/
https://www.ncbi.nlm.nih.gov/pubmed/36686689
http://dx.doi.org/10.3389/fphar.2022.993483

Ejemplares similares