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Echinacoside exerts antidepressant-like effects through enhancing BDNF-CREB pathway and inhibiting neuroinflammation via regulating microglia M1/M2 polarization and JAK1/STAT3 pathway

The present study was performed to investigate the antidepressant effect of echinacoside (ECH) using chronic unpredictable mild stress (CUMS) induced depression mice and lipopolysaccharide (LPS)-stimulated N9 microglial cells. CUMS treatment was performed on C57BL/6 mice for 28 days, followed by gav...

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Detalles Bibliográficos
Autores principales:	Lu, Renrui, Zhang, Li, Wang, Huihui, Li, Meng, Feng, Weisheng, Zheng, Xiaoke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846169/ https://www.ncbi.nlm.nih.gov/pubmed/36686689 http://dx.doi.org/10.3389/fphar.2022.993483

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