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Mechanism and effects of STING–IFN-I pathway on nociception: A narrative review

Since the discovery of STING in 2008, numerous studies have investigated its functions in immunity, inflammation, and cancer. STING activates downstream molecules including IFN-I, NLRP3, and NF-κB. The STING–IFN-I pathway plays a vital role in nociception. After receiving the upstream signal, STING...

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Detalles Bibliográficos
Autores principales: Yang, Jinghan, Ding, Hui, Shuai, Bo, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846240/
https://www.ncbi.nlm.nih.gov/pubmed/36683857
http://dx.doi.org/10.3389/fnmol.2022.1081288