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CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response

Clinically, xenotransplantation often leads to T-cell-mediated graft rejection. Immunosuppressive agents including polyclonal regulatory T cells (poly-Tregs) promote global immunosuppression, resulting in serious infections and malignancies in patients. Xenoantigen-expanded Tregs (xeno-Tregs) have b...

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Detalles Bibliográficos
Autores principales: Cao, Lu, Ma, Xiaoqian, Zhang, Juan, Yang, Min, He, Zhenhu, Yang, Cejun, Li, Sang, Rong, Pengfei, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846302/
https://www.ncbi.nlm.nih.gov/pubmed/36644879
http://dx.doi.org/10.1177/09636897221149444