Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells

In this study, Hawthorn oligomic procyanidins extracts (HPOE) were evaluated for their anticancer activity on colorectal cancer. Our results showed that HPOE arrested HCT116 cells cycle at G2/M phase through P53-Cyclin B pathway and promoted apoptosis partly via mitochondrial (Caspase 9-Caspase 3) a...

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Detalles Bibliográficos
Autores principales: Sun, Ya-Sai, Wang, Zi-Wei, Gao, Zhe, Zhao, Wen, Thakur, Kiran, Zhong, Qian, Wei, Zhao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846341/
https://www.ncbi.nlm.nih.gov/pubmed/36686366
http://dx.doi.org/10.1016/j.crfs.2022.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846341/
https://www.ncbi.nlm.nih.gov/pubmed/36686366
http://dx.doi.org/10.1016/j.crfs.2022.05.009

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