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Functional status and spatial interaction of T cell subsets driven by specific tumor microenvironment correlate with recurrence of non-small cell lung cancer

BACKGROUND: The anti-tumoral or pro-tumoral roles of CD4(+) and CD8(+) T cells typify the complexity of T cell subsets function in cancer. In the non-small cell lung cancer (NSCLC), the density and topology of distinct T cell phenotypes at the tumor center (TC) versus the invasive margin (IM) are la...

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Detalles Bibliográficos
Autores principales: Yang, Liying, Zhang, Wei, Sun, Jujie, Yang, Guanqun, Cai, Siqi, Sun, Fenghao, Xing, Ligang, Sun, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846487/
https://www.ncbi.nlm.nih.gov/pubmed/36685566
http://dx.doi.org/10.3389/fimmu.2022.1022638