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Venlafaxine, an anti-depressant drug, induces apoptosis in MV3 human melanoma cells through JNK1/2-Nur77 signaling pathway

Introduction: Venlafaxine is one of the most commonly used anti-depressant and antineoplastic drug. Previous studies have predicted venlafaxine as an anti-cancer compound, but the therapeutic effects of venlafaxine in melanoma have not yet been demonstrated. Nur77 is an orphan nuclear receptor that...

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Detalles Bibliográficos
Autores principales: Niu, Ting, Wei, Zhiying, Fu, Jiao, Chen, Shu, Wang, Ru, Wang, Yuya, Zheng, Ruihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846499/
https://www.ncbi.nlm.nih.gov/pubmed/36686679
http://dx.doi.org/10.3389/fphar.2022.1080412