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Correlation of ERCC5 polymorphisms and linkage disequilibrium associated with overall survival and clinical outcome to chemotherapy in breast cancer

PURPOSE: ERCC5 is a DNA endonuclease and nucleotide excision repair gene; its mutations lead to a lack of activity by this enzyme, causing oxidative DNA damage. This study aimed to assess the role of four selected single nucleotide polymorphisms (SNPs) in ERCC5 and their linkage disequilibrium assoc...

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Detalles Bibliográficos
Autores principales: Khan, Iqra, Masood, Nosheen, Yasmin, Azra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846539/
https://www.ncbi.nlm.nih.gov/pubmed/36686735
http://dx.doi.org/10.3389/fonc.2022.1091514