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Silver-promoted solid-phase guanidinylation enables the first synthesis of arginine glycosylated Samoamide A cyclopeptide analogue

Cyclization and glycosylation serve as effective approaches for enhancing the drug properties of peptides. Distinct from typical glycosylation, atypical arginine N-glycosylation has drawn increasing attention due to its fundamental role in various cellular procedures and signaling pathways. We previ...

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Detalles Bibliográficos
Autores principales: Liang, Bingxin, Li, Rong, Li, Linji, Tang, Ming, Li, Xiang, Su, Chunli, Liao, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846560/
https://www.ncbi.nlm.nih.gov/pubmed/36688048
http://dx.doi.org/10.3389/fchem.2022.1040216