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Deep dive into the immune response against murine mesothelioma permits design of novel anti-mesothelioma therapeutics

Given the need to improve the efficacy of standard-of-care immunotherapy (anti-CTLA-4 + anti-PD-1) in human malignant pleural mesothelioma (hMPM), we thoroughly characterized the immunobiology of the AB12 murine mesothelioma (MM) model, aiming to increase its accuracy in predicting the response of h...

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Detalles Bibliográficos
Autores principales: Stern, Esther, Caruso, Stefano, Meiller, Clément, Mishalian, Inbal, Hirsch, Theo Z., Bayard, Quentin, Tadmor, Carmit T., Wald, Hanna, Jean, Didier, Wald, Ori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846605/
https://www.ncbi.nlm.nih.gov/pubmed/36685577
http://dx.doi.org/10.3389/fimmu.2022.1026185