(63)Cu(I) binding to human kidney (68)Zn(7)-βα MT1A: determination of Cu(I)-thiolate cluster domain specificity from ESI-MS and room temperature phosphorescence spectroscopy

Mammalian metallothioneins (MTs) are important proteins in Zn(II) and Cu(I) homeostasis with the Zn(II) and Cu(I) binding to the 20 cysteines in metal-thiolate clusters. Previous electrospray ionization (ESI) mass spectrometric (MS) analyses of Cu(I) binding to Zn(7)-MT were complicated by significa...

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Detalles Bibliográficos
Autores principales: Melenbacher, Adyn, Heinlein, Lina, Hartwig, Andrea, Stillman, Martin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846682/
https://www.ncbi.nlm.nih.gov/pubmed/36583699
http://dx.doi.org/10.1093/mtomcs/mfac101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846682/
https://www.ncbi.nlm.nih.gov/pubmed/36583699
http://dx.doi.org/10.1093/mtomcs/mfac101

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