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Comprehensive expression analysis with cell-type-specific transcriptome in ALS-linked mutant SOD1 mice: Revisiting the active role of glial cells in disease

Non-cell autonomous mechanisms are involved in the pathogenesis of amyotrophic lateral sclerosis (ALS), an adult neurodegenerative disease characterized by selective motor neuron loss. While the emerging role of glial cells in ALS has been noted, the detailed cell-type-specific role of glial cells h...

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Detalles Bibliográficos
Autores principales: Yamashita, Hirofumi, Komine, Okiru, Fujimori-Tonou, Noriko, Yamanaka, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846815/
https://www.ncbi.nlm.nih.gov/pubmed/36687517
http://dx.doi.org/10.3389/fncel.2022.1045647