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Clonidine use during dexmedetomidine weaning: A systematic review

BACKGROUND: Dexmedetomidine is a centrally acting alpha-2A adrenergic agonist that is commonly used as a sedative and anxiolytic in the intensive care unit (ICU), with prolonged use increasing risk of withdrawal symptoms upon sudden discontinuation. As clonidine is an enterally available alpha-2A ad...

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Detalles Bibliográficos
Autores principales: Rajendraprasad, Sanu, Wheeler, Molly, Wieruszewski, Erin, Gottwald, Joseph, Wallace, Lindsey A., Gerberi, Danielle, Wieruszewski, Patrick M, Smischney, Nathan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846870/
https://www.ncbi.nlm.nih.gov/pubmed/36683967
http://dx.doi.org/10.5492/wjccm.v12.i1.18