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Synthesis of an amantadine-based novel Schiff base and its transition metal complexes as potential ALP, α-amylase, and α-glucosidase inhibitors

A Schiff base ligand HL, (E)-2-((adamantan-1-ylimino)methyl)-6-allylphenol, was synthesized by condensation of amantadine with 3-allyl-2-hydroxybenzaldehyde, followed by the synthesis of its Zn(ii), Co(ii), Cr(iii), and VO(iv) complexes under reflux conditions. The synthesized compounds were compreh...

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Detalles Bibliográficos
Autores principales: Ajaz, Aliya, Shaheen, Muhammad Ashraf, Ahmed, Maqsood, Munawar, Khurram Shahzad, Siddique, Abu Bakar, Karim, Abdul, Ahmad, Nazir, Rehman, Muhammad Fayyaz ur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846949/
https://www.ncbi.nlm.nih.gov/pubmed/36756442
http://dx.doi.org/10.1039/d2ra07051k