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Payload diversification: a key step in the development of antibody–drug conjugates

Antibody–drug conjugates (ADCs) is a fast moving class of targeted biotherapeutics that currently combines the selectivity of monoclonal antibodies with the potency of a payload consisting of cytotoxic agents. For many years microtubule targeting and DNA-intercalating agents were at the forefront of...

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Detalles Bibliográficos
Autores principales: Conilh, Louise, Sadilkova, Lenka, Viricel, Warren, Dumontet, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847035/
https://www.ncbi.nlm.nih.gov/pubmed/36650546
http://dx.doi.org/10.1186/s13045-022-01397-y