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Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses

BACKGROUND: Inflammation, the physiological response to infection and injury, is coordinated by the immune and nervous systems. Interleukin-1β (IL-1β) and other cytokines produced during inflammatory responses activate sensory neurons (nociceptors) to mediate the onset of pain, sickness behavior, an...

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Detalles Bibliográficos
Autores principales: Silverman, Harold A., Tynan, Aisling, Hepler, Tyler D., Chang, Eric H., Gunasekaran, Manojkumar, Li, Jian Hua, Huerta, Tomás S., Tsaava, Tea, Chang, Qing, Addorisio, Meghan E., Chen, Adrian C., Thompson, Dane A., Pavlov, Valentin A., Brines, Michael, Tracey, Kevin J., Chavan, Sangeeta S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847185/
https://www.ncbi.nlm.nih.gov/pubmed/36650454
http://dx.doi.org/10.1186/s10020-022-00590-6