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Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses
BACKGROUND: Inflammation, the physiological response to infection and injury, is coordinated by the immune and nervous systems. Interleukin-1β (IL-1β) and other cytokines produced during inflammatory responses activate sensory neurons (nociceptors) to mediate the onset of pain, sickness behavior, an...
Autores principales: | Silverman, Harold A., Tynan, Aisling, Hepler, Tyler D., Chang, Eric H., Gunasekaran, Manojkumar, Li, Jian Hua, Huerta, Tomás S., Tsaava, Tea, Chang, Qing, Addorisio, Meghan E., Chen, Adrian C., Thompson, Dane A., Pavlov, Valentin A., Brines, Michael, Tracey, Kevin J., Chavan, Sangeeta S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847185/ https://www.ncbi.nlm.nih.gov/pubmed/36650454 http://dx.doi.org/10.1186/s10020-022-00590-6 |
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