Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain

BACKGROUND: Ischemic stroke in white matter of the brain induces not only demyelination, but also neuroinflammation. Peripheral T lymphocytes, especially regulatory T cells (Tregs), are known to infiltrate into ischemic brain and play a crucial role in modulation of inflammatory response there. We p...

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Detalles Bibliográficos
Autores principales: Xu, Bin, Shimauchi-Ohtaki, Hiroya, Yoshimoto, Yuhei, Sadakata, Tetsushi, Ishizaki, Yasuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847196/
https://www.ncbi.nlm.nih.gov/pubmed/36650518
http://dx.doi.org/10.1186/s12974-023-02694-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847196/
https://www.ncbi.nlm.nih.gov/pubmed/36650518
http://dx.doi.org/10.1186/s12974-023-02694-0

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