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A modified high-resolution melting-based assay (HRM) to identify the SARS-CoV-2 N501Y variant

High-resolution melting (HRM) analysis is a PCR–based method that can be used as a screening assay to identify SARS-CoV-2 variants. However, conventional HRM assays hardly detect slight melting temperature differences at the A–T to T–A transversion. As the N501Y substitution results from A–T to T–A...

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Detalles Bibliográficos
Autores principales: Aoki, Akira, Adachi, Hirokazu, Mori, Yoko, Ito, Miyabi, Sato, Katsuhiko, Kinoshita, Masayoshi, Kuriki, Masahiro, Okuda, Kenji, Sakakibara, Toru, Okamoto, Yoshinori, Jinno, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847321/
https://www.ncbi.nlm.nih.gov/pubmed/36681163
http://dx.doi.org/10.1016/j.jviromet.2023.114678