Comparison of CRISPR-Cas9-mediated megabase-scale genome deletion methods in mouse embryonic stem cells

The genome contains large functional units ranging in size from hundreds of kilobases to megabases, such as gene clusters and topologically associating domains. To analyse these large functional units, the technique of deleting the entire functional unit is effective. However, deletion of such large...

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Detalles Bibliográficos
Autores principales: Miyata, Masayuki, Yoshida, Junko, Takagishi, Itsuki, Horie, Kyoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847339/
https://www.ncbi.nlm.nih.gov/pubmed/36448318
http://dx.doi.org/10.1093/dnares/dsac045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847339/
https://www.ncbi.nlm.nih.gov/pubmed/36448318
http://dx.doi.org/10.1093/dnares/dsac045

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