Preclinical evaluation of IAP0971, a novel immunocytokine that binds specifically to PD1 and fuses IL15/IL15Rα complex

BACKGROUND: Currently, cytokine therapy for cancer has demonstrated efficacy in certain diseases but is generally accompanied by severe toxicity. The field of antibody-cytokine fusion proteins (immunocytokines) arose to target these effector molecules to the tumor microenvironment to expand the ther...

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Detalles Bibliográficos
Autores principales: Chen, Jihong, Shen, Ziyou, Jiang, Xiaoling, Huang, Zhenzhen, Wu, Chongbing, Jiang, Dongcheng, Yin, Liusong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847340/
https://www.ncbi.nlm.nih.gov/pubmed/36683766
http://dx.doi.org/10.1093/abt/tbac031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847340/
https://www.ncbi.nlm.nih.gov/pubmed/36683766
http://dx.doi.org/10.1093/abt/tbac031

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