Nuclear SPHK2/S1P induces oxidative stress and NLRP3 inflammasome activation via promoting p53 acetylation in lipopolysaccharide-induced acute lung injury

A bulk of evidence identified that macrophages, including resident alveolar macrophages and recruited macrophages from the blood, played an important role in the pathogenesis of acute respiratory distress syndrome (ARDS). However, the molecular mechanisms of macrophages-induced acute lung injury (AL...

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Detalles Bibliográficos
Autores principales: Gong, Linjing, Shen, Yue, Wang, Sijiao, Wang, Xinyuan, Ji, Haiying, Wu, Xu, Hu, Lijuan, Zhu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847446/
https://www.ncbi.nlm.nih.gov/pubmed/36653338
http://dx.doi.org/10.1038/s41420-023-01320-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847446/
https://www.ncbi.nlm.nih.gov/pubmed/36653338
http://dx.doi.org/10.1038/s41420-023-01320-5

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