Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis

AIMS: (Ultra) Small superparamagnetic iron oxide nanoparticles, (U)SPIO, are widely used as magnetic resonance imaging contrast media and assumed to be safe for clinical applications in cardiovascular disease. As safety tests largely relied on normolipidaemic models, not fully representative of the...

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Detalles Bibliográficos
Autores principales: Segers, Filip M E, Ruder, Adele V, Westra, Marijke M, Lammers, Twan, Dadfar, Seyed Mohammadali, Roemhild, Karolin, Lam, Tin Sing, Kooi, Marianne Eline, Cleutjens, Kitty B J M, Verheyen, Fons K, Schurink, Geert W H, Haenen, Guido R, van Berkel, Theo J C, Bot, Ilze, Halvorsen, Bente, Sluimer, Judith C, Biessen, Erik A L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847560/
https://www.ncbi.nlm.nih.gov/pubmed/35325057
http://dx.doi.org/10.1093/cvr/cvac032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847560/
https://www.ncbi.nlm.nih.gov/pubmed/35325057
http://dx.doi.org/10.1093/cvr/cvac032

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